Chronic, Relapsing Polyneuropathy
Brother is a 7 month old, neutered male, domestic long hair cat. Brother was presented to Dr. Hause for posterior limb ataxia of about a weeks duration. He has recently become unable to jump onto the bed. His rear limbs will occasionally slip out from underneath him. He is otherwise normal. His owner reported she slammed a door on him a month ago but did not appear to hurt him. His physical abnormalities were confined to the nervous system. He had moderate posterior paresis. His conscious proprioception was diminished in both rear legs. He walked with his rear feet plantigrade. His reflexes were all very hyporeflexive. His flexor withdrawal was diminished. No hyperpathia was found. Initial testing consisted of routine bloodwork which was normal including normal CPK. A myasthenia gravis titer was sent to UCSD and reported negative several days later. An electromyographic examination was performed with Brother under anesthesia. Persistent positive sharp waves were found in the gastrocnemius muscles of both limbs with a few in the cranial tibial muscle. There was no decrement conduction and the nerve conduction velocity was 105 M/second. The assessment of the EMG examination is that there is a polyneuropathy of the motor nerves of the rear limbs present. The diagnosis of this case is Chronic, Relapsing Polyneuropathy. Bensfield AC, et. al. Reported a syndrome of Recurrent demyelination and remyelination in 37 young Bengal cats with polyneuropathy in the J Vet Intern Med. 2011 Jul-Aug;25(4):882-9. These cat had similar histories to Brother’s and recovery from the symptoms was common although they could relapse.